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KMID : 0605620160230030108
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Journal of Korean Society of Biological Psychiatry
2016 Volume.23 No. 3 p.108 ~ p.115
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Aggression and Neurotransmitters
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Yu Si-Young
Choi Ye-Jee
Kim Sang-Joon
Jeong Hyeon-Seok
Ma Ji-Young
Kim Young-Hoon
Moon So-Hyeon
Kang Il-Hyang
Jeong Eu-Jin
Suh Chae-Won
Shin Kyung-Shik
Kim Ji-Eun
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Abstract
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Aggression and aggressive behaviors, often explained as harmful social interaction with the intention of hurting or inflicting damage upon another, have been considered as an adaptive mechanism from the evolutionary psychological point of view. However, various studies on aggression and aggressive behaviors have been done with psychopathological approach as the extreme aggressive behaviors may harm themselves and others at the same time. Recently, researchers have attempted to explain aggression in terms of neurobiological substrates rather than based on traditional psychopathological and/or behavioral concept. In this regard, there have been findings of differences in neurotransmitters and their receptors, and genetic polymorphisms. In this review article, we provide a brief overview of the literature about seven most frequently reported neurotransmitters including neurohormones (serotonin, norepinephrine, dopamine, gamma-aminobutyric acid, nitric oxide, oxytocin and vasopressin) and an associated enzyme (monoamine oxidase A), which are known to be related with aggression and aggressive behaviors.
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KEYWORD
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Aggression, Aggressive behavior, Neurobiology, Genetic
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